In the beginning, the varmints live in harmony with nature. One day, the nature is destroyed and a city is constructed. One varmint saves one branch of tree and keeps it alive. The plant grows seeds and the seeds fly away, eventually saving the world.
I think that the story was optimistic about the future. It shows how nature is strong, and can return to what it once was. However, it cannot do so alone. It needs help. For I think that is what the snow like thing falling from the sky. The varmints were kept away until the earth returned to what it used to be.
One thing I felt while watching the short film was sympathy for the varmints who suffered from asthma. I once to had an asthma attack, and it was very frightening. The scene where the poor varmint was wheezing made that memory come back quite vividly. The harm pollution can do to one's health is quite terrifying, and I think that was one thing the animation was telling us.